Simon, age 62, has had type 2 diabetes for 6 months; it was diagnosed following an admission to hospital with chest pain, which was subsequently diagnosed as angina. He has a BMI of 42kg/m2, and although he has managed to lose some wieight, this has plateaued. His latest HbA1c is 59mmol/mol and he is treated with metformin 2g daily. He has normal renal function. Which class of drugs would offer Simon improvement in his glycaemic control, whilst supporting him to lose weight given that he has established cardiovascular disease.
