This website is intended for healthcare professionals only
User log in

Trial log in

Cardiovascular considerations in patients with type 2 diabetes

This promotional module has been initiated, funded and reviewed solely by Boehringer Ingelheim. The content of this industry-supported learning activity has been generated by Practice Nurse.

Links to prescribing information can be found at the foot of this page. 



The goals of treatment for type 2 diabetes are to prevent or delay complications and maintain quality of life.1 According to some international guidelines, this requires control not only of blood glucose levels, but also cardiovascular risk factor management.1,2

Diabetes is an independent risk factor for atherosclerotic cardiovascular disease (ASCVD) and most people with type 2 diabetes will have additional cardiovascular risk factors such as smoking, obesity, hypertension, dyslipidaemia and physical inactivity.1 A multifactorial and simultaneous risk factor management strategy has lead to reductions in both ASCVD events and deaths in patients with diabetes.1 Guidelines from the European Sociey of Cardiology recommend that this multifactorial approach to diabetes management (encompassing blood pressure, lipid profile, platelet inhibition, smoking cessation, physical activity, weight and dietary habits) should be considered in patients with diabetes and cardiovascular disease (CVD).3

Taking this into account, the choice of drug after metformin is becoming increasingly complex: the prescriber needs to consider cardiovascular risk, renal function and other factors such as hypoglycaemia risk, weight, patient comorbidities including frailty, and patient adherence to treatment.1

This module looks at the increased risk of cardiovascular disease (CVD) associated with type 2 diabetes, the role of pharmacotherapy in managing the condition in line with current guidelines, and provides an overview of the Cardiovascular Outcome Trials (CVOTs) for different medicine classes for patient with type 2 diabetes.


On completion of this module, you will:

  • Be familiar with the association between type 2 diabetes and cardiovascular complications
  • Be aware of the evidence from the cardiovascular outcomes trials of agents used in the management of type 2 diabetes
  • Understand the latest guidance for the pharmacological management of type 2 diabetes
  • Appreciate the importance of a patient-centred approach to management

This module is one of a series of five. Others in the series are:

This resource is provided at an intermediate level. Read the article and answer the self-assessment questions, and reflect on what you have learned.

Complete the resource to obtain a certificate to include in your revalidation portfolio. You should record the time spent on this resource in your CPD log.


1. Davies MJ, D’Alessio D, Fradkin J. Management of hyperglycemia in T2DM, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2018;41:2669-2701

2. Buse JB, Wexler DJ, Tsapas A. 2019 Update to: Management of hyperglycemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2020;43(2):487–493

3. Consentino F, Grant PJ, Aboyans V, et al. 2019 ESC Guidelines on diabetes, pre-diabetes and cardiovascular diseases developed in collaboration with the EASD. Eur Heart J 2020;41:255–323 

Job Code: PC-GB-105045

Date of preparation: July 2022

You can sign up here to receive and manage your electronic communications from Boehringer Ingelheim and its agents acting on its behalf, about BI's products, services and events.

Click here for Trajenta (linagliptin) Prescribing Information: Great Britain | Northern Ireland

Click here for Jardiance (empagliflozin) Prescribing Information: Great Britain | Northern Ireland

Adverse events should be reported. Reporting forms and information can be found at Adverse events should also be reported to Boehringer Ingelheim Drug Safety on 0800 328 1627 (freephone).