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Adverse drug reactions: A guide for general practice nurses

Content developed by Clarity Informatics, providers of online solutions to support the nursing community through appraisals and revalidation.


An adverse drug reaction (ADR) may be a known effect of the drug, or a new and previously unrecognised effect. It is defined as an unwanted or harmful reaction that occurs after administration, and which is suspected or known to be due to the drug. ADRs may also be an unintended or unexpected reaction to a drug normally used for prevention or treatment of a condition. The precise incidence of ADRs is not known with any certainty because it is difficult to assess what caused a reaction, and not all ADRs are reported.


On completion of this module you will have a better understanding of:

  • The definition of an adverse drug reaction (ADR)
  • How common they are
  • Which drugs are most commonly involved
  • The range of differential diagnoses
  • How to manage ADRs
  • Who to discuss or tell about ADRs including Yellow Card reporting

This resource is provided at an advanced level by Clarity Informatics. Read the article and answer the self-assessment questions, and reflect on what you have learned.

Complete the resource to obtain a certificate to include in your revalidation portfolio. You should record the time spent on this resource in your CPD log.